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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Not specified
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: pre-GLP study
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1967
Report date:
1967

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No remarks
GLP compliance:
no
Remarks:
pre-GLP
Test type:
other: not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3,7-dimethylnona-1,6-dien-3-ol
EC Number:
233-732-6
EC Name:
3,7-dimethylnona-1,6-dien-3-ol
Cas Number:
10339-55-6
Molecular formula:
C11H20O
IUPAC Name:
3,7-dimethylnona-1,6-dien-3-ol
Details on test material:
Ethyllinalool, no further information

Test animals

Species:
mouse
Strain:
other: CFW
Sex:
male
Details on test animals or test system and environmental conditions:
Weight: 17-22 g

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
unchanged (no vehicle)
Details on oral exposure:
72 hours observation for mortality
Doses:
Not indicated
No. of animals per sex per dose:
5
Control animals:
not specified
Details on study design:
No remarks
Statistics:
Not indicated

Results and discussion

Preliminary study:
Not indicated
Effect levels
Key result
Sex:
male
Dose descriptor:
LD50
Effect level:
5 283 mg/kg bw
Mortality:
The oral LD50 in mice was determined to be 5283 +/- 383 mg/kg bw.
LD50's were calculated by the method of Miller and Tainter (Proc. Soc. Exptl. Biol. Med. 57:261, 1944).
Clinical signs:
Not indicated
Body weight:
Not indicated
Gross pathology:
Not indicated
Other findings:
Not indicated

Any other information on results incl. tables

Not relevant

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The substance does not have to be classified according to the classification criteria outlined in 67/548/EEC and 1272/2008/EC.
Executive summary:

The oral LD50 in mice was determined to be 5283 +/- 383 mg/kg bw.