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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
04 February 2014 - 17 February 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance
Temp.:
25 °C
Vapour pressure:
0 Pa

Table 1: Summary of Results

Run

Log10 [Vp(25 °C)]

Correlation (r²)

2

-7.05

0.979

3

-7.00

0.959

4

-7.60

0.957

5

-7.15

0.963

6

-6.73

0.947

7

-8.76

0.990

8

-7.84

0.979

9

-7.65

0.988

10

-7.70

0.976

Mean

-7.50

-

Vapour Pressure

3.19 x 10 -8 Pa

-

Run 1 has not been reported as the data generated showed that the vapour pressure had not settled down from initial start up, producing an erratic result not consistent with the other data.

The vapour pressure of the test material has been determined to be 3.2 x 10-8 Pa at 25 ºC, using the vapour pressure balance method.

Conclusions:
Under the conditions of the test the vapour pressure of the test material was determined to be 3.2 x 10-8 Pa at 25 °C, using the vapour pressure balance method.
Executive summary:

The vapour pressure of the test material was determined in a GLP study performed according to EU Test Method A4 and OECD guideline 104, using the vapour pressure balance method.

The vapour pressure was determined using a vapour pressure balance. The temperature of the sample was controlled electronically. The mass and temperature readings were recorded automatically into a computer file.

After evacuating the system, opening the shutter above the sample oven causes the escaping vapour jet to be directed at the scale pan. The difference in mass readings with the orifice covered and uncovered is proportional to the vapour pressure at the given oven temperature.

Preliminary runs were undertaken over the temperature range 20 to 248 °C to provide information for a suitable temperature range for the determination.

A sequence of ten runs was started after a sample of test material had been under vacuum for approximately 216.5 hours. Temperature and pressure readings were taken between 200 and 210 °C with a one hour dwell at 200 °C between runs.

Run 1 has not been reported as the data generated showed that the vapour pressure had not settled down from initial start up, producing an erratic result not consistent with the other data.

Under the conditions of the test, the vapour pressure of the test material has been determined to be 3.2 x 10-8 Pa at 25 °C.

Description of key information

The vapour pressure of the test material has been determined to be 3.2 x 10-8 Pa at 25 °C.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

In the key study the vapour pressure of the test material was determined under GLP conditions and performed in accordance with EU Test Method A4 and OECD guideline 104, using the vapour pressure balance method. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

The vapour pressure was determined using a vapour pressure balance. The temperature of the sample was controlled electronically. The mass and temperature readings were recorded automatically into a computer file.

After evacuating the system, opening the shutter above the sample oven causes the escaping vapour jet to be directed at the scale pan. The difference in mass readings with the orifice covered and uncovered is proportional to the vapour pressure at the given oven temperature.

Preliminary runs were undertaken over the temperature range 20 to 248 °C to provide information for a suitable temperature range for the determination.

A sequence of ten runs was started after a sample of test material had been under vacuum for approximately 216.5 hours. Temperature and pressure readings were taken between 200 and 210 °C with a one hour dwell at 200 °C between runs.

Run 1 has not been reported as the data generated showed that the vapour pressure had not settled down from initial start up, producing an erratic result not consistent with the other data.

Under the conditions of the test, the vapour pressure of the test material has been determined to be 3.2 x 10-8 Pa at 25 °C.