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EC number: 214-189-4 | CAS number: 1112-39-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the justification for grouping of substances provided in IUCLID Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 126 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 126 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Conclusions:
- An LC50 (96 h) of >126 mg/L and a NOEC (96 h) of ≥126 mg/L have been determined for the effects of the source substance on mortality of the fish species Oncorhynchus mykiss in a study according to OECD guideline 203 and GLP. The source substance is the hydrolysis product of the target substance. Since the hydrolysis half life is < 1 h, the results derived for the source substance describe additionally the effects of the the target substance.
Reference
Description of key information
LC50 (96 h) >126 mg/L (OECD 203; Oncorhynchus mykiss); read across from hydrolysis product (dimethylsilanediol)
Key value for chemical safety assessment
Additional information
Experimental data for
dimethoxydimethylsilane (CAS 1112-39-6) are not available. However,
since dimethoxydimethylsilane hydrolyses rapidly to dimethylsilanediol
and methanol (DT50 < 0.6 h) the hydrolysis products rather than the
parent substance should be considered for the assessment, read-across
data for the hydrolysis product, dimethylsilanediol, are considered
appropriate for the assessment.The available study with the freshwater
fish Oncorhynchus mykiss was performed according to OECD 203 (GLP). Fish
were exposed to dimethylsilanediol under static conditions to a nominal
limit concentration of 120 mg/L for 96 h (Dow Corning Corporation,
2009a). The concentrations in test solution were verified by HPLC/RID
analysis and confirmed that the substance is stable. Since no effects on
mortality were recorded the LC50 (96 h) was derived to be > 126 mg/L
(measured arithmetic mean).
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