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Ecotoxicological information

Long-term toxicity to fish

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Reference
Endpoint:
fish early-life stage toxicity
Data waiving:
other justification
Justification for data waiving:
other:

Description of key information

The chemical safety assessment according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to further investigate the long-term toxicity to fish.

Key value for chemical safety assessment

Additional information

The chemical safety assessment according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to further investigate the long-term toxicity to fish.
The available studies on the target substance dimethoxydimethylsilane (CAS 1112-39-6) as well as on the silanol hydrolysis product dimethylsilanediol did not indicate aquatic toxicity to any trophic level tested. Based on the experimental results fish is not considered to be less sensitive than invertebrates or algae. Thus, a long-term study with fish is not considered to be required in addition to the available dataset.
The available effect concentrations were used to derive the PNEC aqua (freshwater) which was used to perform the environmental risk assessment. As a result all risk characterization ratios (RCRs) were clearly <1 indicating no risk to the aquatic compartment.
Taking the low toxicity to aquatic organisms, the results from the environmental risk assessment and animal welfare into account, an additional chronic study with fish is not considered necessary to conclude on the chemical safety of dimethoxydimethylsilane.