Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 214-189-4 | CAS number: 1112-39-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial arthropods: long-term
- Data waiving:
- exposure considerations
- Justification for data waiving:
- other:
Reference
Description of key information
In accordance with REACH Annex XI, Section 3, exposure of terrestrial organisms to dimethoxydimethylsilane is not significant (RCR << 1) and the substance has a low hazard potential based on the available acute data.
Key value for chemical safety assessment
Additional information
In accordance with Annex XI, Section 3, exposure of terrestrial organisms to dimethylsilanediol is not significant. A study testing the long-term toxicity of the silanol hydrolysis product, dimethylsilanediol, on the respiration and nitrogen transformation of soil microflora is available. No chronic effects were observed in this study for the silanol hydrolysis product on the respiration rate and nitrate formation rate of soil microflora (90-day NOEC≥300 mg/kg soil dw).
Furthermore, the hazard assessment based on acute aquatic toxicity data shows no toxicity toward aquatic organisms of all three trophic levels (all acute effect values, i.e. E(L)C50s were > 100 mg/L). Additionally, a chronic toxicity test on aquatic invertebrates is available, which showed no effects up to the highest tested concentration (21-day NOEC ≥ 12.6 mg/L). The substance is well soluble and thus, greater toxicity in additional long-term tests is unlikely.
Even though no hazard was identified in acute aquatic studies and the available chronic terrestrial study, PNECs aqua and a PNEC soil were derived for the purpose of risk characterization, using the threshold value of 12.6 mg/L derived from the chronic daphnia study in combination with standard safety factors as outlined in ECHA guidance R.10. A PNEC soil was calculated based on the equilibrium partitioning method. As the substance hydrolyses rapidly, the environmental hazard assessment, PNEC soil derivation and risk characterization is based on the silanol hydrolysis product following a worst case approach. The other hydrolysis product, methanol, is known for its absence of environmental toxicity (OECD SIDS, 2004). The risk characterization for the silanol hydrolysis product indicated no risk to the aquatic environment (RCR < < 1).
For detailed information on the risk assessment please see the attached documentation.
References:
OECD SIDS, 2004: SIDS Initial Assessment Report for Methanol, SIAM 19, Berlin, Germany, 19-22 October 2004, Methanol, CAS 67-56-1Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

EU Privacy Disclaimer
This website uses cookies to ensure you get the best experience on our websites.