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EC number: 271-653-9 | CAS number: 68603-38-3 This substance is identified by SDA Substance Name: C16-C18 and C18 unsaturated alkyl carboxylic acid amide diethanol and SDA Reporting Number: 11-024-00.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
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- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
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- Endpoint summary
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- Environmental data
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- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
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- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
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- Biological effects monitoring
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- Toxicological Summary
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- Irritation / corrosion
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- Carcinogenicity
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- Exposure related observations in humans
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- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
- Amides, C8-18(even-numbered) and C18-unsatd., N,N-bis(hydroxyethyl) also called amides, C8-18 and C18-unsatd., N,N-bis(hydroxyethyl)
- Amides, C12-18(even-numbered) and C18 -unsatd., N,N-bis(hydroxyethyl) also called amides, C12-18 and C18 -unsatd., N,N-bis(hydroxyethyl)
- Lauric acid diethanolamine condensate (LDEA, CAS No. 120-40-1)
- Amides, C18-unsatd., N,N-bis(hydroxyethyl)
- DEA-derived FAA substances all share a common functional group (i.e., fatty acid alkanolamide) and constituents, with only variable carbon range numbers, i.e., the basic structure and functional groups are the same.
- DEA-derived FAA substances all have common constituents, i.e., incremental and constant change across the category relating to the physical-chemical properties (e.g., melting/boiling point; Kow; Koc; water solubility; environmental distribution characteristics).
General discussion of environmental fate and pathways:
This chemical safety report characterizes the hazards and risks associated with the use ofamides, C16-18(even-numbered) and C18-unsatd., N,N-bis(hydroxyethyl),a diethanolamine-derived fatty acid alkanolamide (“DEA-FAA”) in which fatty acids are bound to diethanolamine (DEA) by an amide bond.The alkyl chain length typically ranges between 16 and 18 carbon atoms.Grouping hypothesis and justification of read-across adopted
Data for amides, C16-18(even-numbered) and C18 -unsatd., N,N-bis(hydroxyethyl) has been supplemented with safety data from structurally similar fatty acid alkanolamides based on the read-across approach of grouping substances (category approach) and from supporting substances (structural analogue or surrogate) using data from the following DEA-FAA substances:
The grouping hypothesis and therefore the read-across approach adopted are based on the following characteristics of DEA-derived FAA substance:
The use of data from the “DEA-FAA” category is justified due to structural similarities as indicated by a common functional group (i. e., fatty acid alkanolmide) and comparable fate properties: DEA-FAA are all readily biodegradable and expected to degrade by the same pathways involving omega- and beta oxidation finally leading to complete mineralization.
The structural similarity of “DEA-FAA” results in similar physico-chemical properties such as water solubility and octanol-water partition coefficient as well as similar expected biodegradation pathways.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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