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Long-term toxicity to aquatic invertebrates

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Description of key information

The 21 day NOEC and LOEC of structurally similar amides, C12-18(even-numbered) and C18-unsatd., N,N-bis(hydroxyethyl) for effects on reproduction and survival rates of Daphnia magna were 0.07 and 0.24 mg/L (based on the arithmetical mean measured concentrations of the nominal concentration of 0.1 and 0.32 mg/L), respectively.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.07 mg/L

Additional information

A study was conducted to evaluate the effect of structurally similar amides, C12 -18(even-numbered) and C18 -unsatd., N,N-bis(hydroxyethyl) on survival and reproduction ofDaphnia magnaaccording to OECD guideline 211.

Daphnia magna(10 per dose) were exposed to the test substance in nominal concentration ranges of 0.010 - 1.0 mg/L for 21 days and effects on survival and reproduction were determined three times per week. The corresponding analytically determined concentrations at nominal test concentrations of 0.10 and 0.32 mg/L were 0.07 and 0.24 mg/L, respectively.

Under the test conditions, the 21 d NOEC and LOEC of the test substance for effects on reproduction and survival rates ofDaphnia magnawere 0.07 and 0.24 mg/L (based on the arithmetical mean measured concentrations of the nominal concentration of 0.1 and 0.32 mg/L), respectively.

(Memmert U, 1995).