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Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22.11.2000 - 17.1.2001
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001
Report date:
2001

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
10-methoxy-5H-dibenz[b,f]azepine
EC Number:
225-172-6
EC Name:
10-methoxy-5H-dibenz[b,f]azepine
Cas Number:
4698-11-7
Molecular formula:
C15H13NO
IUPAC Name:
10-methoxy-5H-dibenzo[b,f]azepine

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Duration of test (contact time):
28 d
Initial test substance concentration
Initial conc.:
12 mg/L
Based on:
other: TOC
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
CO2 evolution

Results and discussion

% Degradation
Parameter:
% degradation (CO2 evolution)
Value:
< 5
Sampling time:
28 d
Details on results:
In the toxicity control more than 25% degradation occurred within 14 days (based on ThC02). Therefore, the test substance was assumed to be not inhibitory.

Applicant's summary and conclusion

Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
The test substance was not readily biodegradable under the condition of the modified Sturm test presently performed.