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Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Meets scientific standards

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005

Materials and methods

Type of study / information:
Occupational exposure measurements
Endpoint addressed:
not applicable
Principles of method if other than guideline:
Occupational monitoring
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
no details

Method

Ethical approval:
not applicable
Details on study design:
Personal monitoring was conducted for MVE between the years of 1982 and 2004 in the MVE manufacturing unit in South Charleston, WV and in the Specialty Products unit in Taft, LA. The objective was to evaluate potential exposures during various shifts and tasks for a variety of similar exposure groups.
Exposure assessment:
measured
Details on exposure:
Monitoring was performed for groups assessed to have potential for exposure to MVE for the purpose of applying exposure controls, assigning personal protective equipment, and verification of compliance with the company internal exposure guidelines.
Over the 22-year period, the exposure groups with potential for exposure consistently included outside and inside operators, one "weigh operator", maintenance personnel, Union rail tank car operators, and laboratory personnel.

Results and discussion

Results:
Results for all job assignments and tasks ranged from 0.001 ppm to 2.1 ppm, and the geometric mean for all exposures is 0.26 ppm (standard deviation 5.95 ppm), and the 95% upper confidence limit is 1.34 ppm.
Area emission monitoring results, although not indicative of personal exposure, were non-detected at the limit of quantitation (0.37-0.02 ppm).

Applicant's summary and conclusion