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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

Lethal Concentration 0% (LC0): 21.5 mg/L

Lethal Concentration 50% (LC50): 76.1 mg/L

Lethal Concentration 100% (LC100): 100 mg/L

Key value for chemical safety assessment

LC50 for freshwater fish:
76.1 mg/L

Additional information

The acute toxicity of 1,4 -Butynediol (B3D) to freshwater fish has been tested according to various guideline and non-guideline methods under non-GLP conditions. Tests results with Klimisch scores of at least 2 yielded 96 hr LC50 values of 53.6 mg/L (Veith, et. al., 1989) to 76.1 mg/L (Tisler, et. al., 2003), and a 96 hr NOEC of 21.5 mg/L and LC100 of 100 mg/L (BASF AG, 1988). These data indicate that 1,4 -Butynediol is moderately toxic to freshwater fish.