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Short-term toxicity to aquatic invertebrates

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Description of key information

No effects up to the water solubility limit (< 1 mg/L) for aquatic invertebrates (OECD 202/ISO 14669).

Key value for chemical safety assessment

Additional information

Two short-term studies with Daphnia magna, freshwater invertebrates, and one short-term test with Acartia tonsa, a marine invertebrate, forFatty acids, C8-10 (even), C14-18 (even) and C16-18 (even)-unsatd., triesters with trimethylolpropane (former CAS 85186-89-6), are available. In both static GLP-freshwater studies equivalent or similar to OECD 202 no immobilised daphnids or other adverse reactions could be observed for an exposure period of 48 hours (key: EL0 ≥ 100 mg/L, EL50 > 100 mg/L; supporting: NOELR ≥ 1000 mg/L, EL50 > 1000 mg/L). Because of the serial dilution in the supporting study from the highest concentration (1000 mg/L), only the 1000 mg/L test concentration was valid and could be used for evaluation of toxicity of the test substance. In the static GLP-saltwater study (Hudson, 2005) according to ISO 14669 (Determination of acute lethal toxicity to marine copepods) no immobilisation was determined during the 48 h test duration (NOELR ≥ 10000 mg/L, EL50 > 10000 mg/L). Therefore, no toxicities in the range of water solubility (< 1 mg/L) were observed for freshwater and marine invertebrates.