Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Carcinogenicity

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Administrative data

Endpoint:
carcinogenicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
97 WK
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: http://actor.epa.gov/actor/GenericChemicalPdfServlet?casrn=99-59-2

Data source

Reference
Reference Type:
study report
Title:
Unnamed

Materials and methods

Test material

Constituent 1
Reference substance name:
5-nitro-o-anisidine
EC Number:
202-770-5
EC Name:
5-nitro-o-anisidine
Cas Number:
99-59-2
IUPAC Name:
2-methoxy-5-nitroaniline

Test animals

Species:
mouse
Strain:
B6C3F1
Sex:
female

Administration / exposure

Route of administration:
oral: unspecified
Details on analytical verification of doses or concentrations:
0; 0.8% IN DIET FOR 78 WK
Duration of treatment / exposure:
(STUDY DURATION: 97 WK)
Doses / concentrations
Remarks:
Doses / Concentrations:
0; 0.8% IN DIET FOR 78 WK
Basis:

Results and discussion

Effect levels

Sex:
female
Remarks on result:
other: Effect type: carcinogenicity (migrated information)

Applicant's summary and conclusion

Conclusions:
Results : NEGATIVE