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Hydrolysis

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Hydrolysis is a common degradation route in the environment, where reaction of a substance with water with a net exchange of the X group with an OH at the reaction centre such that RX + H2O → ROH + HX. Hydrolysis is often dependent upon pH as the reaction is commonly catalysed by hydrogen or hydroxide ions. Hydrolysis kinetics are usually determined experimentally and should be used to consider the test type and whether parent or degradation product should be tested. For the substance, also confirmed by calculation with HYDROWIN 2.0, it can be estimated that hydrolysis does not occur because there is not hydrolysable groups in the structure. Hydrolyzable organic groups are in fact those groups that can react with water like Esters, Anhydrides, Amides, Carbammates, Nitriles, Cyanates, Epoxides, Halomethanes, Alkylhalides, Urea and none of these groups are present within the substance or their impurities.

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