Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics, other
Remarks:
evaluation of existing test and data
Type of information:
other: Expert Judgement
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
other: expert judgement
Title:
Unnamed
Year:
2017

Materials and methods

Objective of study:
absorption
distribution
excretion
metabolism
toxicokinetics
Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Expert judgement with evaluation of toxicokinetic, metabolism and excretion.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium 8-phenylamino-5-(4-(3-sulphonatophenylazo)-1-naphthylazo)naphthalenesulphonate
EC Number:
222-111-5
EC Name:
Sodium 8-phenylamino-5-(4-(3-sulphonatophenylazo)-1-naphthylazo)naphthalenesulphonate
Cas Number:
3351-05-1
Molecular formula:
C32H23N5O6S2.2Na
IUPAC Name:
NA
Test material form:
solid: particulate/powder
Radiolabelling:
yes

Results and discussion

Metabolite characterisation studies

Metabolites identified:
yes

Applicant's summary and conclusion

Conclusions:
Not bioaccumulative
Executive summary:

Based on the data available, Acid Yellow 23 undergoes to a metabolic degradation into metabolites which are excreted by urine and faeces and therefore Acid Yellow 23 can be considered as not-bioaccumulative.

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