Registration Dossier
Registration Dossier
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EC number: 222-111-5 | CAS number: 3351-05-1
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics, other
- Remarks:
- evaluation of existing test and data
- Type of information:
- other: Expert Judgement
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- other: expert judgement
- Title:
- Unnamed
- Year:
- 2 017
Materials and methods
- Objective of study:
- absorption
- distribution
- excretion
- metabolism
- toxicokinetics
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Expert judgement with evaluation of toxicokinetic, metabolism and excretion.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Sodium 8-phenylamino-5-(4-(3-sulphonatophenylazo)-1-naphthylazo)naphthalenesulphonate
- EC Number:
- 222-111-5
- EC Name:
- Sodium 8-phenylamino-5-(4-(3-sulphonatophenylazo)-1-naphthylazo)naphthalenesulphonate
- Cas Number:
- 3351-05-1
- Molecular formula:
- C32H23N5O6S2.2Na
- IUPAC Name:
- disodium 8-(phenylamino)-5-[(1E)-2-{4-[(1E)-2-(3-sulfonatophenyl)diazen-1-yl]naphthalen-1-yl}diazen-1-yl]naphthalene-1-sulfonate
- Test material form:
- solid: particulate/powder
Constituent 1
- Radiolabelling:
- yes
Results and discussion
Metabolite characterisation studies
- Metabolites identified:
- yes
Applicant's summary and conclusion
- Conclusions:
- Not bioaccumulative
- Executive summary:
Based on the data available, Acid Yellow 23 undergoes to a metabolic degradation into metabolites which are excreted by urine and faeces and therefore Acid Yellow 23 can be considered as not-bioaccumulative.
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