Cyclohexyl methacrylate

Acute Toxicity: inhalation

Administrative data

Endpoint:

acute toxicity: inhalation

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference

Reference Type:

publication

Title:

Monomeric methyl methacrylate studies on toxicity

Author:

Spealman C.R., Main R.J., Haag H.B., Larson P.S.

Year:

1945

Bibliographic source:

Ind. Med. 14: 292-298

Materials and methods

Principles of method if other than guideline:

Study to assess the acute inhalative toxicity in mice.

GLP compliance:

no

Limit test:

no

Test material

Test material information

Constituent 1

Reference substance name:

Methyl methacrylate

EC Number:

201-297-1

EC Name:

Methyl methacrylate

Cas Number:

80-62-6

Molecular formula:

C5H8O2

IUPAC Name:

methyl methacrylate

Test animals

Species:

mouse

Strain:

not specified

Sex:

not specified

Administration / exposure

Route of administration:

inhalation

Type of inhalation exposure:

not specified

Vehicle:

not specified

Duration of exposure:

3 h

Results and discussion

Effect levels

Effect levels 1

Key result

Dose descriptor:

LC50

Effect level:

55 mg/L air

Exp. duration:

3 h

Remarks on result:

other: 55.0 mg/L equals 13220 ppm

Effect levels 2

Dose descriptor:

LC100

Effect level:

61.8 mg/L air

Exp. duration:

3 h

Remarks on result:

other: 61.8 mg/L equals 14860 ppm

Effect levels 3

Dose descriptor:

other: LC5

Effect level:

26.2 mg/L air

Exp. duration:

3 h

Remarks on result:

other: 26.2 mg/L equals 6300 ppm

Effect levels 4

Dose descriptor:

other: LC13

Effect level:

47.7 mg/L air

Exp. duration:

3 h

Remarks on result:

other: 47.7 mg/L equals 11470 ppm