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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer reviewed data

Data source

Reference
Reference Type:
review article or handbook
Title:
Documentation of the Threshold Limit Values and Biological Exposure Indices.
Author:
American Conference of Governmental Industrial Hygienists, Inc.
Year:
1991
Bibliographic source:
6th ed. Volumes I, II, III. Cincinnati, OH: ACGIH

Materials and methods

Principles of method if other than guideline:
No data

Test material

Constituent 1
Chemical structure
Reference substance name:
Chloroacetyl chloride
EC Number:
201-171-6
EC Name:
Chloroacetyl chloride
Cas Number:
79-04-9
Molecular formula:
C2H2Cl2O
IUPAC Name:
chloroacetyl chloride

Test animals

Species:
rat

Administration / exposure

Route of administration:
inhalation
Duration of exposure:
4 h

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
1 000 ppm

Applicant's summary and conclusion

Interpretation of results:
Toxicity Category III
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
LC50 Rat inhalation 1000 ppm/4 hr
Executive summary:

LC50 Rat inhalation 1000 ppm/4 hr