Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 242-670-9 | CAS number: 18917-91-4
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 21-day-chronic toxicity of Aluminium chloride to Daphnia magna was studied under static renewal conditions. The 21 day EC16 (based on reproduction) was 320 µg Al/L (nominal) or recalculated to Aluminium trilactate 3489.28 µg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3.489 mg/L
Additional information
No data on long term toxicity to aquatic invertebrates are available for the substance Aluminium trilactate. Aluminium trilactate will dissociate into Lactic acid and Aluminium ions in aqueous solutions. Thus a read-across to the the moieties of Aluminium trilactate - Lactic acid and Aluminium is used for hazard assessment.
No data are available for long term effects of Lactic acid to aquatic invertebrates. From other aquatic toxicity studies it has become clear, that Al is the more critical moiety. Thus, the lacking data for lactic acid are not considered to be of concern.
Long term toxicity of Aluminium to aquatic invertebrates has also been reviewed by Environment Canada (2010), WHO IPCS EHC (1997) and US ATSDR (2008). These reviews and the literature cited therein have also been taken into account for hazard assessment.
The 21-day-chronic toxicity of Aluminium chloride to Daphnia magna was studied under static renewal conditions (tested concentrations not given in the publication). The 21 day LC50 and EC50 based on mortality and reproduction were 1400 and 680 µg Al/L(nominal), respectively.
The 21 day EC16 (based on reproduction) was 320 µg Al/L(nominal) or recalculated to Aluminium trilactate 3489.28 µg/L.
References:
Environment Canada (2010) Environment Canada Priority Substance List Assessment Report, Follow-up to the State of Science Report, 2000 Aluminium Salts (Final Content), available via internet: http://www.ec.gc.ca/lcpe-cepa/default.asp?lang=En&n=491F0099-1 and http://www.ec.gc.ca/lcpe-cepa/documents/substances/sa-as/final/al_salts-eng.pdf
US ATSDR (United States Agency for Toxic Substances and Disease Registry) (2008) Toxicological profile for Aluminium, U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, Public Health Service, Agency for Toxic Substances and Disease Registry, available via internet: http://www.atsdr.cdc.gov/toxprofiles/tp.asp?id=191&tid=34
WHO IPCS EHC (World Health Organisation International Programme on Chemical Safety Environmental Health Criteria) (1997) Aluminium (Environmental health criteria; 194), IPCS, World Health Organization, Geneva, available via internet: http://www.inchem.org/documents/ehc/ehc/ehc194.htm
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
