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Short-term toxicity to aquatic invertebrates

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Description of key information

An OECD TG 202 guideline study in compliance with GLP criteria with Daphnia magna is is available for the test substance. In this study Daphnids (20/concentration) were exposed to nominal concentrations of 0, 10, 18, 32, 56 and 100 mg/L under static conditions for 48 hours. Samples for confirmation of the exposure concentrations were taken at the start and at the end of the exposure. After the 48-hour exposure period test concentrations were analysed to be 8.99, 15.7, 30.3, 53.6 and 93.5 mg/L (87 - 96% of nominal). The study met the acceptability criteria prescribed by the protocol and was considered valid. No immobilisation was observed in the control. The percentage of immobile daphnids increased from 5% at 10 mg/L to 100% at 32, 56 and 100 mg/L. Based on these results, the 48-h EC50 was determined to be 15 mg/L (95% C.L.: 13 - 17 mg/L) based on the analytically confirmed nominal concentrations.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Dose descriptor:
Effect concentration:
15 mg/L

Additional information