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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Description of key information

Cyclohexylamine has a measured log Kow of 3.7 at a temperature o f 25 °C and a pH value of 6.8. (Currenta, 2010)

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
25 °C

Additional information

In case more than 10 % of the test item is dissociated at pH 6, a second test has to be performed at a pH where the test item is undissociated. The pKa value of the test item Cyclohexylamine accounts for 10.68 (Perrin, 1965) having the nonionic form solely at pH values approximately greater 11. As the prescribed analytical column for the HPLC method is not suitable for strong basic conditions (outside operating range), the measurement was performed at pH 6 only.

Based on the dissociation constant of 10.68 (Perrin, 1965), the substance will, under environmental relevant conditions (pH 4 to 9), be present solely in the protonated form. Therefore, the measured logKow reflects the properties of the protonated form rather than the neutral species and thus the properties of the environmental relevant species.