Registration Dossier
Registration Dossier
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EC number: 203-629-0 | CAS number: 108-91-8
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- publication
- Title:
- Studies on toxicity and skin effects of compounds used in the rubber and plastics industries
- Author:
- Mallette FS, Von Haam E.,
- Year:
- 1 952
- Bibliographic source:
- Arch. Ind. Hyg. Occup. Med.|5, 311-317
Materials and methods
- Type of study / information:
- in vivo skin irritation experiment with volunteers
- Principles of method if other than guideline:
- patch-testing method. Not less than 15 individuals were tested. The material was placed by patch on the skin of the back and remained for 48 hours.
- GLP compliance:
- no
Test material
- Reference substance name:
- Cyclohexylamine
- EC Number:
- 203-629-0
- EC Name:
- Cyclohexylamine
- Cas Number:
- 108-91-8
- Molecular formula:
- C6H13N
- IUPAC Name:
- cyclohexanamine
- Details on test material:
- no further data
Constituent 1
Method
- Ethical approval:
- not specified
- Details on study design:
- patch-testing method. Not less than 15 individuals were tested. The material was placed by patch on the skin of the back and remained for 48 hours.
- Exposure assessment:
- measured
- Details on exposure:
- patch-testing method. Not less than 15 individuals were tested. The material was placed by patch on the skin of the back and remained for 48 hours.
25 % solution
Results and discussion
- Results:
- the voluteers showed severe irritational effects (no further details given)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
