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Additional toxicological data

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additional toxicological information
Type of information:
other: relationship cyclohexylamine and cyclamate
Adequacy of study:
other information

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Reference Type:
publication
Title:
The metabolism of cyclamate to cyclohexylamine in humans during long-term administration
Author:
Renwick AG et al
Year:
2004
Bibliographic source:
Toxicol appl Pharmacol 196, 367-380
Reference Type:
publication
Title:
In vivo conversion of C-labelled cyclamate to cyclohexylamine
Author:
Parosky L et al
Year:
1971
Bibliographic source:
J Pharmacol Sci 60, 1341-2343
Reference Type:
publication
Title:
The metabolism of cyclamates in rats
Author:
Wallace WC, Kethco EJ, Brouwer EA
Year:
1970
Bibliographic source:
J Pharmacol Exp Toxicol 175, 325-330
Reference Type:
publication
Title:
a 7-month study of ingestion of socium cyclamate by human volunteers
Author:
Wills JH, Serrone DM, Coulston F
Year:
1981
Bibliographic source:
Regul toxicol Oharmacol 1, 163-176
Reference Type:
publication
Title:
Beitrag zur hygienischen Beurteilung von Cyclamat
Author:
Wolf A et al
Year:
1971
Bibliographic source:
Die Nahrung 15, 363.366
Reference Type:
publication
Title:
Long-term toxicits and carcinogenicity study of cyclamate in nonhuman primates
Author:
Takayama S, Renwick AG, Johansson SL, Thorgeirsson UP, Tsutsumi M, Dalgard DW, Sieber SM
Year:
2000
Bibliographic source:
Tox Sci 53, 33-39
Reference Type:
publication
Title:
Cyclamate intake and cyclohexylamine excretion are not related to male fertility in humans
Author:
Serra-Majem L et al
Year:
2003
Bibliographic source:
Food Add Contam 20, 1097-1194
Reference Type:
publication
Title:
Possible mutagenic activity of saccharin
Author:
Renner HW
Year:
1979
Bibliographic source:
Experientia 35, 1364-1365
Reference Type:
publication
Title:
Excretion of cyclohexylamine, a metabolite of cyclamate in human urine
Author:
Asahina M et al
Year:
1971
Bibliographic source:
Chem Pharm Bull 19, 628-632
Reference Type:
publication
Title:
Entero-bacterial formation of cyclohexylamine in rats ingesting cyclamate
Author:
Bickel MH et al
Year:
1974
Bibliographic source:
Xenobiotical 4, 425-439

Materials and methods

Results and discussion

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