Registration Dossier

Administrative data

Description of key information

Based on the available information cyclohexylamine has corrosive properties.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (corrosive)

Additional information

Skin irritation/corrosion studies indicate that cyclohexylamine has corrosive properties. In one study undiluted test substance was applied to the back of rabbits for 1, 5 min and 20 hours and the animals were observed for up to 8 days after exposure. Necrosis (observed at 24 h and 8 days) was reported after 1 min exposure and marked necrosis after 5 min. After 20 h exposure marked necrosis rounded by significant erythema was observed (BASF 1970). Additional studies mentioned in the IUCLID dossier support that cyclohexylamine has corrosive properties.

Single application of undiluted testsubstance into the conjunctival sac of one rabbits indicated that cyclohexylamine was corrosive to the mucouse membraines, caused hemorrhage and severe not reverible lesions (BASF 1970).


Effects on skin irritation/corrosion: corrosive

Justification for classification or non-classification

According to the EU classification criteria 67/548/EWG Annex 1 the compound is classified with R34. According to EU regulation no. 790/2009 (GHS) the compound is classified Skin Corr 1B.