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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

HAT-ISO was tested for aquatic toxicity in a number of tests including EU-Method C.1, Acute toxicity to fish, EU-Method C.2, Acute toxicity to Daphnia and EU-Method C.3, Acute toxicity to algae. Following results were obtained: 

Acute toxicity to fish in the test with Brachydanio rerio revealed a 96 h LD50 of > 250 mg/L (nominal concentration). The 96 h-NOEC in the fish toxicity test was > 250 mg/L (nominal concentration).

Acute toxicity to aquatic invertebrates in the test with Daphnia magna revealed a 48 h EC50 of > 100 mg/L (nominal concentration). The 48 h-NOEC in the Daphnia toxicity test was > 100 mg/L (nominal concentration).

Acute toxicity to freshwater green algae was investigated in two studies. In the key study, toxicity to aquatic algae Desmodesmus subspicatus revealed a 72 h EC50 (growth rate) of > 100 mg/L (nominal concentration). The 72 h-NOEC in the algae inhibition test was > 100 mg/L (nominal concentration). In the supporting study, the 72 h EC50 (growth rate) to Desmodesmus subspicatus was determined to be ca. 76 mg/L (nominal concentration), with a 95 % confidence interval of 54 to 108 mg/L. This value was regarded as invalid, as post testing analysis of the test material revealed that the batch used for testing was contaminated with solvent residues.

The toxicity of HAT-ISO to microorganisms was tested in a 3 h activated sludge respiration inhibition test. The 3 h EC 50 was determined to be > 100 mg/L (nominal concentration). HAT-ISO was considered non-toxic to aquatic microorganisms.

In summary, none of the aquatic toxicity studies revealed toxicity of the test material HAT-ISO. Further testing of HAT-ISO, e.g. in long-term toxicity tests, was considered not scientifically justified.