Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 211-750-5 | CAS number: 693-36-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects occur at the range of solubility.
Key value for chemical safety assessment
Additional information
Two experimental studies are available.
In a new GLP guideline study according to OECD 201 (2017) with Pseudokirchneriella subcapitata saturated solutions with different loading rates were tested under consideration of OECD Guidance document on aquatic toxicity testing of difficult items and mixtures. Up to the highest test concentration no adverse effects on algae, growth and yield were observed. Concentration control analysis revealed that the highest test concentration were above the water solubility of < 4 μg/L.
In a supporting non-GLP guideline study using Scenedesmus subspicatus as test organism, an EC50 of 60 mg/L for biomass was determined. Lecithin was used as a solvent, however in a very high concentration 0.4 mg/L, which is above the vehicle limit of present guidelines. Almost 30 % of algae were inhibited in the solvent control (1992, Report 928155).
The data were re-evaluated to determine the effects on growth rate. In the test the ErC10 and ErC50 were above the water solubility. (ErC10(72h) = 73 mg/L. For further details on this re-evaluation see the corresponding attachment in the endpoint study record.
The effect concentrations are well above the solubility limit of the test substances (water solubility < 4 μg/L, see chapter 4.8 in IUCLID). In conclusion, the substance shows no effect to aquatic algae in the range of water solubility.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
