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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

Acutely harmful to aquatic invertebrates.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Dose descriptor:
EC50
Effect concentration:
45 mg/L

Additional information

To determine the toxicity of morpholine to aquatic invertebrates, a study following OECD 202 using Daphnia magna was performed according to GLP. The test animals were exposed under semi-static conditions Based on nominal, analytically verified test concentrations a 48-h EC50 of 45 mg/L was determined (NITE, 1997). This value was selected as key data.


In conclusion, morpholine is assessed to be acutely harmful to aquatic invertebrates.