Registration Dossier
Registration Dossier
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EC number: 212-751-3 | CAS number: 866-81-9
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Most sensitive long-term toxicity data for 3 different freshwater fish species are summarized in the WHO CICAD document (2006). According to these data, the effect concentrations for cobalt hydrogencitrate were calculated:
Brachydanio rerio: no effect concentration (16d, survival) = 0.19 mg Tricobalt dicitrate/L
Pimephales promelas: NOEC (7d, survival) = 6.25 mg Tricobalt dicitrate/L
Oncorhynchus mykiss: NOEC (14d, growth) = 0.31 mg Tricobalt dicitrate/L
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.19 mg/L
Additional information
Data on chronic single-species toxicity tests resulting in high quality NOEC/L(E)C10 values (expressed as Co) for freshwater fish (n= 21) are summarised in Table 2 of the WHO CICAD document, 2006 (see attached document).
Chronic data for 3 different fish species were extracted and used in the effects assessment. The NOEC/L(E)C10 values for fish range from 60 μg Co/L for Brachydanio rerio (data shown in the study record in detail) to 2000 μg Co/L for Pimephales promelas(Diamond et al., 1992), resulting in recalculated values from 0.19 to 6.25 mg Tricobalt dicitrate/L. The most sensitive
data for Brachydanio rerio are shown in detail in the key study record of chap 6.1.2, further results for other freshwater fish are attached here.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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