Registration Dossier
Registration Dossier
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EC number: 200-471-4 | CAS number: 60-34-4
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion, other
- Remarks:
- general observations
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Patty's Toxicology
- Author:
- Bingham, E.; Cohrssen, B.; Powell, C.H
- Year:
- 2 001
- Bibliographic source:
- Volumes 1-9 5th; p. V4 1294; ed. John Wiley & Sons
Materials and methods
- Principles of method if other than guideline:
- No data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methylhydrazine
- EC Number:
- 200-471-4
- EC Name:
- Methylhydrazine
- Cas Number:
- 60-34-4
- Molecular formula:
- CH6N2
- IUPAC Name:
- methylhydrazine
Constituent 1
Results and discussion
In vivo
Results
- Remarks on result:
- probability of severe irritation
Applicant's summary and conclusion
- Interpretation of results:
- Category 1B (corrosive) based on GHS criteria
- Conclusions:
- Methylhydrazine can produce severe skin and eye damage in animal models and would be expected to perform similarly in humans.
- Executive summary:
Methylhydrazine can produce severe skin and eye damage in animal models and would be expected to perform similarly in humans.
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