Registration Dossier
Registration Dossier
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EC number: 200-471-4 | CAS number: 60-34-4
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion, other
- Remarks:
- general observations
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Patty's Toxicology
- Author:
- Bingham, E.; Cohrssen, B.; Powell, C.H
- Year:
- 2 001
- Bibliographic source:
- Volumes 1-9 5th; p. V4 1294; ed. John Wiley & Sons
Materials and methods
- Principles of method if other than guideline:
- No data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methylhydrazine
- EC Number:
- 200-471-4
- EC Name:
- Methylhydrazine
- Cas Number:
- 60-34-4
- Molecular formula:
- CH6N2
- IUPAC Name:
- methylhydrazine
Constituent 1
Results and discussion
In vivo
Results
- Remarks on result:
- probability of severe irritation
Applicant's summary and conclusion
- Interpretation of results:
- Category 1B (corrosive) based on GHS criteria
- Conclusions:
- Methylhydrazine can produce severe skin and eye damage in animal models and would be expected to perform similarly in humans.
- Executive summary:
Methylhydrazine can produce severe skin and eye damage in animal models and would be expected to perform similarly in humans.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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