Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data from IUCLID dataset

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
2000

Materials and methods

Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium hydrogen 4-amino-5-hydroxynaphthalene-2,7-disulphonate
EC Number:
226-736-4
EC Name:
Sodium hydrogen 4-amino-5-hydroxynaphthalene-2,7-disulphonate
Cas Number:
5460-09-3
Molecular formula:
C10H8NO7S2.Na
IUPAC Name:
sodium hydrogen 4-amino-5-hydroxynaphthalene-2,7-disulfonate

Method

Species / strain
Species / strain / cell type:
other: Salmonella typhimurium TA1535, TA1537, TA1538, TA98, TA100
Metabolic activation:
with and without
Metabolic activation system:
S9

Results and discussion

Test results
Species / strain:
S. typhimurium, other: TA1535, TA1537, TA1538, TA98, TA100
Metabolic activation:
with and without
Genotoxicity:
negative
Remarks on result:
other: other: Salmonella typhimurium TA1535, TA1537, TA1538, TA98, TA100
Remarks:
Migrated from field 'Test system'.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
negative

not mutagenic