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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study

Data source

Reference
Reference Type:
publication
Title:
Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects
Author:
Michael Cleuvers
Year:
2003
Bibliographic source:
Toxicology Letters 142, p.185-194

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.3 (Algal Inhibition test)
Deviations:
no
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium [2-[(2,6-dichlorophenyl)amino]phenyl]acetate
EC Number:
239-346-4
EC Name:
Sodium [2-[(2,6-dichlorophenyl)amino]phenyl]acetate
Cas Number:
15307-79-6
Molecular formula:
C14H11Cl2NO2.Na
IUPAC Name:
sodium {2-[(2,6-dichlorophenyl)amino]phenyl}acetate

Test organisms

Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Results and discussion

Effect concentrations
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
72 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate

Applicant's summary and conclusion

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