Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-736-8 | CAS number: 149-30-4
Repeated dose toxicity: other routes
Administrative data
- Endpoint:
- short-term repeated dose toxicity: other route
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only secondary literature available
Data source
Referenceopen allclose all
- Reference Type:
- other: cited in BG Chemie 2000
- Title:
- Toxicity of a rubber accelerator
- Author:
- Guess, W., L.; et al.
- Year:
- 1 969
- Bibliographic source:
- Toxicol. Appl. Pharmacol., 14, 221-231
- Reference Type:
- publication
- Title:
- Toxikologische Bewertung 2-Mercaptobenzothiazol, Nr. 70, CAS Nr. 149-30-4
- Author:
- BG Chemie
- Year:
- 2 000
- Bibliographic source:
- Berufsgenossenschaft der chemischen Industrie, ISSN 0937-4248
Materials and methods
- Principles of method if other than guideline:
- other: subacute toxicity study
Test material
- Reference substance name:
- Benzothiazole-2-thiol
- EC Number:
- 205-736-8
- EC Name:
- Benzothiazole-2-thiol
- Cas Number:
- 149-30-4
- Molecular formula:
- C7H5NS2
- IUPAC Name:
- 1,3-benzothiazole-2-thiol
- Details on test material:
- MBT
Constituent 1
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- intraperitoneal
- Duration of treatment / exposure:
- 1 week
- Frequency of treatment:
- daily
Doses / concentrations
- Remarks:
- Doses / Concentrations:
0, 55, 110 mg/kg bw
- No. of animals per sex per dose:
- 10 per dose
- Control animals:
- yes
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
Gross pathology: no effects
Effects on the liver and kidney, no effects on lung, heart, testis and thyroid gland
hexobarbital-induced sleeping phase extended
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
