Registration Dossier
Registration Dossier
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EC number: 203-453-4 | CAS number: 107-02-8
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Freshwater invertebrates
Daphnia magna three generation study: 64 d NOEC=0.0169 mg/l
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.017 mg/L
Additional information
1. European Union Risk Assessment Report of Acrolein (EU, 2001)
Fresh water
For Daphnia magna a three generation 64-days NOEC-value of 16.9 μg/l is reported. It has to be noted that the long exposure time of 64 days is not according to the recommended exposure time of the OECD guidelines (14 or 28 days).
In addition a long-term NOEC value is available for the mollusc Dreissena polymorpha. However the NOEC (mortality) of 1800 μg/l is derived in a 14 days experiment, which may be considered relatively short for a long-term test with this species (average life time of D. polymorpha is about two years).
Marine invertebrates
Long-term toxicity data for marine invertebrates are not available.
2. Agreement with further international Reports and Studies published after finalisation of the EU Risk Assessment Report 2001
WHO (2002): In a 64-day exposure of the zooplankton Daphnia magna, 100% mortality occurred in the F2 generation at 42.7 μg/litre. The NOEC for survival was estimated to be 16.9 μg/litre. In another study, a subchronic 14-day NOEC of 1800 μg/litre was derived for the mollusc Dreissena polymorpha.
3. Substantial disagreements in comparison to further international Reports to European Union Risk Assessment Report 2001
None
4. Additional aspects in further international Reports
None
5. Additional information in newer Studies, not included in the European Union Risk Assessment Report 2001 or further cited international reports
None
6. Conclusions
The lowest reported effect concentration in a three generation study is a 64-days NOEC-value of 16.9 μg/l for Daphnia magna.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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