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Short-term toxicity to aquatic invertebrates

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Description of key information

Parent compound: No data available
Hydrolysis product: Acutely harmful to aquatic invertebrates.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
51.25 mg/L

Additional information

Parent compound isobutyryl chloride and hydrolysis product isobutyric acid:

No data are available for the test substance isobutyryl chloride (CAS 79 -30 -1). The substance rapidly decomposes in water and forms HCl (CAS 7647 -01 -0) and isobutyric acid (CAS 79 -31 -2). Therefore, the short-term toxicity to aquatic invertebrates is assessed on the basis of data on isobutyric acid.The toxicity of isobutyric acid (CAS 79 -31 -2) was tested on the waterflea Daphnia magna in a 48-h acute immobilization test according to German Industrial Standard Guideline DIN 38412, part 11 at concentrations of 0 (water control), 15.625, 31.3, 62.5, 125, 250, and 500 mg/L. Immobilization and other toxic effects were observed 3, 6, 24, and 48 h after initiation of the test. The 48-h EC50 was determined to be 51.25 mg/L (BASF AG, 1989). Based on the results of the read across substance isobutyric acid the test substance isobutyryl chloride is supposed to be acutely harmful to Daphnia magna.

Hydrolysis producthydrochloric acid (HCl):

The hydrolysis product hydrochloric acid (HCl) was tested in a semi-static acute toxicity test according to OECD 202 with Daphnia magna. The 48-h EC50 was 0.492 mg/L (acid equivalent to pH 5.3; OECD 2002).