Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
91 µg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
9.1 µg/L
Assessment factor:
100
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
4.8 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
12.2 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
1.22 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
4.4 mg/kg soil dw
Assessment factor:
10
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential to cause toxic effects if accumulated (in higher organisms) via the food chain

Additional information

Conclusion on classification

The short-term LC50 or EC50 values were 6.7, >14 and 2.5 mg/l, for fish, daphnia and algae, respectively. Therefore, based on the available short-term data, Cyclaprop does not need to be classified for acute aquatic toxicity according EU CLP (EC 1272/2008 and its amendments).

For Cyclaprop adequate chronic toxicity data are available for three trophic levels. According to the EU CLP, Figure 4.1.1, in case chronic test data are available for all three trophic levels, the chronic classification should be determined based on data from chronic tests. The lowest NOEC / EC10 from these chronic tests is a 33d-EC10 of 0.91 mg/L for fish. Therefore, based on the available chronic data in combination with its non-rapidly degradability, Cyclaprop needs to be classified as H411 according to EU CLP (EC 1272/2008 and its amendments).

For GHS: The acute toxicity of 2.5 mg/l results in Acute Cat. 2 (H401).