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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

With high probability acutely not harmful to aquatic invertebrates.

Key value for chemical safety assessment

Additional information

In a GLP guideline study following the EU Method C.2 (Acute Toxicity for Daphnia) waterflea (Daphnia magna) were exposed for 48 hours in a static test to 'Hexamethylene diisocyanate, oligomerisation product (biuret type)'. The study was conducted as a limit test with nominal test concentration of 100 mg/L in the water accomodated fraction (WAF). The EL50 (48h) was >= 100 mg/L nominal test substance concentration (Bayer AG, 2000).