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Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Insufficient for assessment; compounded rubber stocks tested

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1961

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
Principles of method if other than guideline:
other: Repeated Insult Patch Test
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N'-bis(1,4-dimethylpentyl)-p-phenylenediamine
EC Number:
221-375-9
EC Name:
N,N'-bis(1,4-dimethylpentyl)-p-phenylenediamine
Cas Number:
3081-14-9
Molecular formula:
C20H36N2
IUPAC Name:
N1,N4-bis(5-methylhexan-2-yl)benzene-1,4-diamine
Details on test material:
Dialkyl-p-phenylenediamine sheeting

Method

Type of population:
general
Route of administration:
dermal

Results and discussion

Results of examinations:
0/50 volunteers showed positive skin reactions

Applicant's summary and conclusion