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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1969
Report date:
1969

Materials and methods

Principles of method if other than guideline:
other: acute toxicity study
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N'-bis(1,4-dimethylpentyl)-p-phenylenediamine
EC Number:
221-375-9
EC Name:
N,N'-bis(1,4-dimethylpentyl)-p-phenylenediamine
Cas Number:
3081-14-9
Molecular formula:
C20H36N2
IUPAC Name:
N1,N4-bis(5-methylhexan-2-yl)benzene-1,4-diamine
Details on test material:
N,N'-Di (1,4)-dimethyl-penthyl-p-phenylendiamin (NA 5)

Test animals

Species:
mouse

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
175 other: mm3
Based on:
test mat.
Remarks on result:
other: clinical signs

Any other information on results incl. tables

Clinical signs: dyspnose, spasmodic convulsion, prone position, increased weakness

Applicant's summary and conclusion