Registration Dossier
Registration Dossier
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EC number: 305-500-5 | CAS number: 94581-02-9 Coke formed by cooling, to approximately 1500°C, hot acetylene containing split gases from aromatic residual oil produced from ethylene production by naphtha cracking at 800°C to 900°C (427°F to 482°F) (coal derived).
Endpoint summary
Administrative data
Description of key information
LD50 (oral): > 10000 mg/kg bw
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 10 000 mg/kg bw
Additional information
In a pre GLP study comparably performed according to OECD 401 with acceptable restrictions groups of 5 rats per sex and dose were administered with 10,000 mg/kg bw of the test substance (vehicle: aqueous emulsion containing 0.5% carboxy methylcellulose). The dose volume was 20 mL/kg bw (= maximum 4.2 mL/ animal). The acute LD50 for male and female rats is > 10,000 mg/kg. No clinical signs or abnormal necropsy findings were observed (BASF AG, 1978).
Justification for classification or non-classification
Classification for acute toxicity is not warranted according to the criteria of EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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