Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In this study there was no indication for a skin sensitizing potential of sodium perborate monohydrate. Also the degradation products (H2O2 and boron compounds) gave no concern for this endpoint.


Migrated from Short description of key information:
A possible sensitizing potential of sodium perborate monohydrate was tested in a study according to OECD Guideline 406 with Hartley albino guinea pigs. Under the conditions of this study, the test article is a non-sensitizer.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In this study there was no indication for a respiratory sensitizing potential of sodium perborate tetrahydrate.


Migrated from Short description of key information:
In a study with guinea pigs (inhalation exposure to sodium perborate tetrahydrate at 1 hour intervals for a total of 4 hours to 9 mg/m3 or for 1 hour per week for 6 consecutive weeks to 11 mg/m3; 6 weeks after the first exposure both exposure groups were challenged with the same concentration as above for 1 hour) there was no indication that the substance may cause respiratory sensitisation.

Justification for classification or non-classification