Registration Dossier

Administrative data

Endpoint:
dissociation constant
Type of information:
other: handbook data
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer reviewed physico-chemical data

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Journal of the American Chemical Society , 102(21), 6498-6503
Author:
Ball, Sheldon; Bruice, Thomas C
Year:
1980
Bibliographic source:
REAXYSFILE (previously Beilstein database)
Reference Type:
review article or handbook
Title:
Canadian journal of Chemistry 76(6), <1998>, 678 - 685;
Author:
Colthurst, Matthew J.; Kanagasooriam, Angeline J. S. S.; Wong, Michael S. O.; Contini, Christian; Williams, Andrew,
Year:
1998
Bibliographic source:
REAXYSFILE (previously Beilstein database)

Materials and methods

Principles of method if other than guideline:
not specified
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Dissociating properties:
yes
Dissociation constantopen allclose all
No.:
#1
pKa:
-0.75
Temp.:
30 °C
No.:
#2
pKa:
12.88
Temp.:
20 °C

Applicant's summary and conclusion

Conclusions:
the pKa of N,N-diethylhydroxylamine is 12.88 at 20°C