1-nitroguanidine

Toxicity to terrestrial arthropods

Administrative data

Endpoint:

toxicity to terrestrial arthropods: long-term

Data waiving:

exposure considerations

Justification for data waiving:

the study does not need to be conducted because direct and indirect exposure of the soil compartment is unlikely

Justification for type of information:

In accordance with REACH 9.4 Annex IX, column 2, studies on effects on terrestrial organisms do not need to be conducted if direct and indirect exposure of the soil compartment is unlikely. As direct exposure of the soil and indirect exposure of the soil via sewage treatment plants is not expected, no short-term or long-term toxicity testing on invertebrates must be conducted. Moreover, long-term toxicity testing shall be proposed by the registrant if the results of the chemical safety assessment according to Annex I indicate the need to investigate further the effects of the substance and/or degradation products on terrestrial organisms. The choice of the appropriate test(s) depends on the outcome of the chemical safety assessment. Apart from its explosive properties, nitroguanidine is not classified as hazardous. Nitroguanidine is practically non-toxic to aquatic vertebrates and invertebrates, plants, and micro-organisms. Furthermore, nitroguanidine is expected not to accumulate in soil to any extent. Therefore, nitroguanidine poses no hazard to soil-dwelling organisms, and soil-dwelling organisms will not be exposed to nitroguanidine, regardless of its use. Therefore, no long-term toxicity testing of soil organisms is required.