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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: The study is rated a "4" because it predates GLP and limited details are provided.

Data source

Reference
Reference Type:
publication
Title:
Studies on the toxicity of phthalates via ingestion
Author:
Krauskopf, LG
Year:
1973
Bibliographic source:
Environmental Health Perspectives, p 61-72

Materials and methods

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10-rich
EC Number:
271-091-4
EC Name:
1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10-rich
Cas Number:
68515-49-1
Molecular formula:
C28 H46 O4
IUPAC Name:
1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10 rich
Constituent 2
Reference substance name:
1,2-benzenedicarboxylic acid, di-C9,C10 and C11 branched alkyl ester, C10 Rich
IUPAC Name:
1,2-benzenedicarboxylic acid, di-C9,C10 and C11 branched alkyl ester, C10 Rich

Test animals

Species:
other: rat and rabbit

Administration / exposure

Route of administration:
oral: unspecified
Doses:
single dose

Results and discussion

Effect levelsopen allclose all
Sex:
not specified
Dose descriptor:
LD50
Effect level:
29 100 mg/kg bw
Remarks on result:
other: rat
Sex:
not specified
Dose descriptor:
LD50
Effect level:
29 100 mg/kg bw
Remarks on result:
other: rabbit
Mortality:
non-lethal

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
The test substance is assumed to have a low order of acute toxicity by the oral route. The LD50 was reported to be 29,100 mg/kg in rats and in rabbits, a minimum lethal dose of 21,825-29,100 mg/kg has been calculated