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EC number: 244-754-0 | CAS number: 22047-49-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study with acceptable restrictions (analytical purity not specified, no necropsy performed, limited documentation).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 985
- Report date:
- 1985
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- yes
- Remarks:
- analytical purity not specified, no necropsy performed, limited documentation
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 2-ethylhexyl stearate
- EC Number:
- 244-754-0
- EC Name:
- 2-ethylhexyl stearate
- Cas Number:
- 22047-49-0
- Molecular formula:
- C26H52O2
- IUPAC Name:
- 2-ethylhexyl stearate
- Details on test material:
- - Name of test material (as cited in study report): Stearate D'Ethyl 2 Hexyl
- Physical state: no data
- Analytical purity: no data
- Lot/batch No.: 2826
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- other: NMRI EOPS
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Weight at study initiation: 22 g (males) and 20 g (females)
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 4300 mg/kg bw (converted from 5 mL/kg bw, based on a density of 860 g/L)
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 4 300 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: no mortalities observed, converted from 5 mL/kg bw based on a density of 860 g/L, see IUCLID Section "Physical and chemical properties, Density"
- Mortality:
- No mortality occurred during the study period.
- Clinical signs:
- other: No clinical signs occurred during the study period.
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information
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