Registration Dossier
Registration Dossier
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EC number: 209-980-6 | CAS number: 600-00-0
Endpoint summary
Administrative data
Description of key information
Ethyl 2-bromoisobutyrate has to be considered as a serious eye irritant since an experimental study confirm that the substance has the potential to cause severe ocular irritancy.
In addition, Ethyl 2-bromoisobutyrate has to be considered as a moderate irritant (cat.3) according to an experimental study result on rabbit.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
In-vitro study on eye irritation confirm that Ethyl 2-bromoisobutyrate has the potentiel to cause severe ocular irritancy.
An experimental test on rabbits showed that Ethyl 2-bromoisobutyrate is a moderate irritant to skin.
Effects on skin irritation/corrosion: moderately irritating
Effects on eye irritation: highly irritating
Justification for classification or non-classification
Ethyl 2-bromoisobutyrate has to be classified as eye irritant category 1 according to CLP regulation, and the highest hazard statement - H318 : Causes serious eye damage - is then required.
In addition, Ethyl 2-bromoisobutyrate has to be considered as a moderate skin irritant (cat.3) according to ths Globally Harmonised Classification (H316 : causes mild skin irritation). Therefore, this hazard statement has not to be reproduced in the classification of the substance according to CLP regulation.
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