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Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

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Reference
Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
other: expert judgement
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Acceptable, well-documented statement which meets basic scientific principles
Conclusions:
Expert judgement: the substance is stable in common organic solvents; solvents containing a carbonyl moiety may lead to imines formation with primary amines.
Executive summary:

This assessment is based on text-book chemical knowledge and practical handling experience. Primary aliphatic alkyl amines are known to react with carbonyl groups under formation of imines. With respect to common organic solvents not bearing the carbonyl moiety, aliphatic alkyl amines are known to be stable.

Description of key information

Expert judgement: the substance is stable in common organic solvents; solvents containing a carbonyl moiety may lead to imines formation with primary amines.

Additional information

This assessment is based on text-book chemical knowledge and practical handling experience. Primary aliphatic alkyl amines are known to react with carbonyl groups under formation of imines. With respect to common organic solvents not bearing the carbonyl moiety, aliphatic alkyl amines are known to be stable.