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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: No specific test guideline was reported; however, a scientifically defensible approach was used to conduct the study.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1944
Report date:
1944

Materials and methods

Principles of method if other than guideline:
Intravenous injection of different doses.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Magnesium di(acetate)
EC Number:
205-554-9
EC Name:
Magnesium di(acetate)
Cas Number:
142-72-3
Molecular formula:
C2H4O2.1/2Mg
IUPAC Name:
magnesium diacetate
Details on test material:
- Name of test material (as cited in study report): Magnesium acetate.

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Doses:
0.267 mg/20g
0.312 mg/20g
0.367 mg/20g
No. of animals per sex per dose:
0.267 mg/20g: 9 animals
0.312 mg/20g: 7 animals
0.367 mg/20g. 6 animals
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
18 mg/kg bw
Based on:
test mat.

Any other information on results incl. tables

Magnesium acetate intravenous in mouse LD50= 18 mg/kg bw.

Applicant's summary and conclusion

Conclusions:
Magnesium acetate intravenous in mouse LD50= 18 mg/kg bw.
Executive summary:

Magnesium acetate intravenous in mouse LD50= 18 mg/kg bw.