Registration Dossier

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

Currently viewing:

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: No specific test guideline was reported; however, a scientifically defensible approach was used to conduct the study.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1944
Report date:
1944

Materials and methods

Principles of method if other than guideline:
Intravenous injection of different doses.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Magnesium di(acetate)
EC Number:
205-554-9
EC Name:
Magnesium di(acetate)
Cas Number:
142-72-3
Molecular formula:
C2H4O2.1/2Mg
IUPAC Name:
magnesium diacetate
Details on test material:
- Name of test material (as cited in study report): Magnesium acetate.

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Doses:
0.267 mg/20g
0.312 mg/20g
0.367 mg/20g
No. of animals per sex per dose:
0.267 mg/20g: 9 animals
0.312 mg/20g: 7 animals
0.367 mg/20g. 6 animals
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
18 mg/kg bw
Based on:
test mat.

Any other information on results incl. tables

Magnesium acetate intravenous in mouse LD50= 18 mg/kg bw.

Applicant's summary and conclusion

Conclusions:
Magnesium acetate intravenous in mouse LD50= 18 mg/kg bw.
Executive summary:

Magnesium acetate intravenous in mouse LD50= 18 mg/kg bw.