Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Skin irritaton/corrosion: Key study: Read-across from experimental results on the analogue substance Calcium Acetate. Magnesium Acetate did not produce any irritation effect on the rabbit skin. Test method was similar to OECD guideline 404.
Eye irritation/corrosion: Key study: Read-across from experimental results on the analogue substance Calcium Acetate. Magnesium Acetate was not irritating for the eyes of rabbits. Test method was similar to OECD guideline 405.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Skin irritation/corrosion:

Key study:

Read-across approach from experimental results on the analogue substance Calcium Acetate: Test method was similar to OECD guideline 404.

The irritation and corrosive effects of Calcium Acetate acid was studied on Vienna White rabbits (two males and one female).

Animals were exposed for 4 hours to a 50 % aqueous solution and observed for 9 days. Calcium Acetate did not produce any irritation effect on the rabbit skin.

Based on these results, read-across was applied and Magnesium Acetate is considered to be not irritating.

Eye irritation/corrosion:

Key study:

Read-across approach from experimental results on the analogue substance Calcium Acetate: Test method was similar to OECD guideline 405.

The Acute eye irritation test was performed on Vienna White rabbits (males and females). Ca. 53 mg of Calcium Acetate was applied to the conjunctival sac of the right eye of 6 animals. The left eye served as the untreated control. Assessment of the irritant effect was made 1 h, 24 h, 48 h, 72 h, and 8 days after test substance application. Under test conditions, Calcium Acetate was not irritating for the eyes of rabbits.

Based on these results, read-across was applied and Magnesium Acetate is considered to be not irritating.

Justification for classification or non-classification

No irritant.