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Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics
Type of information:
other: theoretical approach
Adequacy of study:
key study
Study period:
21 March, 2012
Reliability:
other: not applicable
Rationale for reliability incl. deficiencies:
other: Study is based on expert judgment.

Data source

Materials and methods

Objective of study:
other: toxicokinetic assessment
Principles of method if other than guideline:
A theoretical approach of the toxicokinetic properties of the substance based on the available physico-chemical properties and toxicological data.

Test material

Constituent 1
Reference substance name:
Diglycerol
IUPAC Name:
Diglycerol
Details on test material:
- Name of test material: diglycerol
- Substance type: organic liquid

Results and discussion

Preliminary studies:
See below
Main ADME results
Type:
absorption
Results:
For risk assessment purposes the following absorption factors were derived: 100% for oral, dermal and inhalation absorption

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): bioaccumulation potential cannot be judged based on study results
For risk assessment purposes the following absorption factors were derived:
oral absorption factor: 100%
dermal absorption factor: 100%
inhalation absorption factor: 100%