Registration Dossier
Registration Dossier
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EC number: 241-460-4 | CAS number: 17439-11-1
Endpoint summary
Administrative data
Description of key information
Skin Sensitisation
Because the substance H2TiF6 is a highly corrosive liquid (Skin Corr. 1, H314: Causes severe skin burns and eye damage), no experimental studies investigating skin sensitisation are available. Further, read-across is applied from the solid salt dipotassium hexafluorotitanate (K2TiF6), which was shown not to be sensitising in a guideline conform study according to OECD Guideline 406 (guinea pig maximisation study, Reference: Hall, D.A. (2013)). No classification for skin sensitisation is required for H2TiF6.
Justification for selection of skin sensitisation endpoint:
Read-across to H2TiF6 (no testing possible because of corrosivity) from non-corrosive salt dipotassium hexafluorotitanate based on structural similarities.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
Justification for classification or non-classification
Skin Sensitisation
Because the substance H2TiF6 is a highly corrosive liquid (Skin Corr. 1, H314: Causes severe skin burns and eye damage), no experimental studies investigating skin sensitisation are available. Further, read-across is applied from the solid salt dipotassium hexafluorotitanate (K2TiF6), which was shown not to be sensitising in a guideline conform study according to OECD Guideline 406 (guinea pig maximisation study, Reference: Hall, D.A. (2013)). No classification for skin sensitisation is required for H2TiF6.
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