Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 284-892-9 | CAS number: 84989-04-8 The fraction of tar acid rich in 3- and 4-methylphenol, recovered by distillation of low-temperature coal tar crude tar acids.
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (96 h) = 5 mg/L on Strongylocentrotus droebachiensis (marine, no guideline)
EC50 (48 h) = 7.7 mg/L on Daphnia magna (freshwater, DIN 38412 part 11)
Key value for chemical safety assessment
Additional information
o-cresol - freshwater
The acute toxicity of o-cresol to Daphnia pulex was determined in a static immobilization test (, 1978). The test was carried out in analogy to a Dutch standard method which is similar to OECD 202. In 3 laboratories duplicate samples with each 25 individuals of <1 day old daphnids were exposed to the test solutions. Analytical confirmation of exposure levels was not performed. After an exposure period of 48 h a nominal EC50 of 9.6 mg/L was found on Daphnia pulex.
m-cresol - freshwater
The acute toxicity of m-cresol to Daphnia pulicaria was determined in an experiment under flow-through conditions (DeGraeve, 1980). Analytical monitoring was performed. Based on measured concentrations a 48h-EC50 > 99.5 mg/L was determined.
p-cresol – freshwater
The short term toxicity of p-cresol to the freshwater invertebrate Daphnia magna was measured according to German Guideline DIN 38412 part 11. The 48-h EC50 was 7.7 mg/L (Kuehn et al. 1989).
m-cresol and p-cresol – marine water
The toxicity of p-cresol and m-cresol to the freshly fertilized eggs of the marine sea urchin Strongylocentrotus droebachiensis was determined by a static test. For p-cresol the 96 -h EC50 was 5 mg/L and for m-cresol the 96-h EC50 was 30 mg/L (Falk-Petersen et al. 1985).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
