Registration Dossier
Registration Dossier
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EC number: 204-876-7 | CAS number: 128-04-1
Toxicity to birds
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to birds: reproduction test
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Description of key information
The chemical safety assessment carried out according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to further investigate the toxicity to birds.
Key value for chemical safety assessment
Additional information
In accordance with column 2 of REACH Annex X, the study on birds does not need to be conducted for sodium dimethyldithiocarbamate (CAS 128-04-1) as sufficient reliable data are available from the mammalian data set showing no toxicity to mammals for long-term toxicity studies, e.g. repeated dose toxicity. In addition, according to Guidance on information requirements and chemical safety assessment, R.7c (ECHA, 2017), a risk for secondary poisoning is unlikely for sodium dimethyldithiocarbamate (CAS 128-04-1) as the substance is readily biodegradable and has a low potential for bioaccumulation in fish and earthworms (log Pow = -3.5 to -2.33). Thus, the substance has a low exposure potential for birds and further investigation of chronic avian toxicity is unnecessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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